Propylthiouracil

What is propylthiouracil?

Propylthiouracil is an anti-thyroid drug used to treat hyperthyroidism.

It can also be used to prepare patients for surgical or radioactive iodine correction of hyperthyroidism.

How should I give my child propylthiouracil?

Follow these instructions when giving your child propylthiouracil:

• Give this medicine regularly, as directed.
• Give this medicine at evenly spaced intervals throughout the day.

What should I do if my child misses a dose of propylthiouracil?

• Give the missed dose as soon as you remember.
• If it is almost time for the next dose, skip the missed dose. Give your child the next dose at the regular time.
• Give your child only one dose at a time.

What are the possible side effects of propylthiouracil?

Notify the doctor if your child continues to have any of the following symptoms or if these symptoms become bothersome:

• itching
• abnormal hair loss
• abnormal colouring of the skin
• swelling of the feet, arms, or face
• nausea
• vomiting
• stomach upset
• loss of taste sensation
• headache
• drowsiness

Contact your doctor immediately if your child has:

• unexplained fever
• unusual bruising or bleeding
• skin rash

What other important information should I know about propylthiouracil?

• Store the medicine at room temperature in a well closed container. Do not keep it where it is exposed to heat or humidity. Do NOT store it in the bathroom or kitchen.
• Your child's doctor may suggest that you avoid giving your child foods that are high in iodine. Some examples of iodine-rich foods are seafood and iodized table salt.
• Tell the doctor if your child is taking medications to control seizures (anticonvulsants).
• Keep a list of all medications your child is on and show the list to the doctor or pharmacist.
• Do not share your child's medicine with others. Do not give anyone else's medicine to your child.
• Make sure you always have enough propylthiouracil to last through weekends, holidays, and vacations. Call your pharmacy at least 2 days before your child runs out of medicine to order refills.
• Do not keep any medicines that are out of date. Check with your pharmacist about the best way to throw away outdated or leftover medicines.
  

Keep propylthiouracil out of your child’s sight and reach and locked up in a safe place. If your child takes too much propylthiouracil, call your local Poison Information Centre at one of these numbers. These calls are free. 

• Call 1-844 POISON-X, or 1-844-764-7669, from anywhere in Canada except Quebec.
• Call 1-800-463-5060 if you live in Quebec.